Antidepressants that work purely on serotonin are effective in reducing OCD symptoms which suggests serotonin may be involved in OCD. OCD symptoms form part of conditions that are known to be biological in origin; degenerative brain disorder: Parkinson's disease, which causes muscle tremors and paralysis (Nestadt). If a biologial disorder produces OCD symptoms, we may assume that biology underlies OCD. This suggests that biological factors may also be responsible for OCD.