PAPILLOMAVIRUSES
Virus: Human Papilloma Virus
Characteristics: dsDNA circular; icosahedral capsid; no envelope (100
Transmission: Direct contact, sexual contact for genital warts
Site of latency: Epithelial tissue (Infect squamous cells and induce
formation of cytoplasmic vacuole (koilocytes)
Disease: Skin and Genital warts, benign head and neck tumors, anogenital
Diagnosis: Cytology, DNA probes, HPV antigen
Treatment: Surgical or chemical removal; podophyllin
Prevention: Vaccination (Gardasil and Cervarix) – 9-16 y.o,
barrier contraception, avoid contact w/ infected skin