limitation serious side effects. Although drugs like SSRIs help people most of the time, small pop no benefit. Some may experience side effects such as blurred vision, indigestion and many others. usually temporary,can be distressing for people, and for a few minority the side effects long lasting. clients taking tricyclic clomipramine side effect common and serious. 1 in 10 can face weight gain and 1 in 100 more aggressive heart problems. This means that some people can experience a reduced quality of life due to taking these drugs and may stop taking them all together cease to be effective.