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Module 5
5.2.2 Respiration
Glycolysis
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Glycolysis involves the splitting of one molecule of
glucose
into
two
smaller molecules of
pyruvate.
Glycolysis occurs in the
cytoplasm
of cells.
Glycolysis is the first stage of both
aerobic
and
anerobic
respiration and doesn't need
oxygen
to take place.
First, APT is used to
phosphrylate glucose
to
triose phosphate
which is then
oxidised
, releasing
ATP.
Glycolysis has a net gain of
2
ATP
Glucose is originally
phosphorylated
by adding 2
phosphates
from
2
molecules of ATP (which become
ADP
)
Once
glucose
is phosphorylated one molecule of hexose
bisphosphate
is made.
Hexose bisphosphate is split into
2
molecules of
triose phosphate
which then loses
hydrogen
forming
2
molecules of
pyruvate.
NAD collects the
hydrogen
ions from the
oxidation
of triose phosphate to form
reduced
NAD.
4
ATP is produced, but
2
were used up in stage 1 so there is a net gain of
2
ATP.