Wants to remove femininity 4
The 'fall of man' is a central idea of a tragedy, for a religious Jacobean audience this would be reflective of the archetype, the story of Adam and Eve.
Eve was tempted by Satan in the form of a serpent to eat the forbidden fruit (much like Lady Macbeth being tempted by the witches' allusion to Kingship).
Eve ate the fruit and convinced Adam to do the same, resulting in their downfall of them both, they were banished from the Garden of Eden. It could be argued that Lady Macbeth, much like Eve, set the foundation for her husband's evil.