Control of gene expression

    Cards (9)

    • Transcription factors are proteins that regulate gene expression by binding to specific DNA sequences near the promoter region, either activating or repressing transcription initiation.
    • Eukaryotic genes have multiple regulatory elements within their non-coding regions, including enhancers (positive regulators) and silencers/repressors (negative regulators).
    • The promoter region is the site where RNA polymerase binds to initiate transcription.
    • The regulation of gene expression is complex and involves multiple layers of control at different stages of the process.
    • Different cell types have distinct patterns of gene expression due to differences in their epigenomes.
    • Epigenetic modifications such as histone acetylation can also affect gene expression without changing the underlying DNA sequence.
    • Enhancer elements can be located far away from the promoter but still influence transcription factor binding and RNA polymerase activity.
    • The regulation of eukaryotic gene expression is more complex than prokaryotes due to the presence of introns and alternative splicing events.
    • Enhancer elements can be located far away from the promoter but still influence transcriptional activity.
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