Specific immune response

• Describe the inflammatory response

  • Pathogens damage cells/tissue
  • WBC called mast cells
  • Release histamines
  • Cause vasodilation of arterioles
  • Increasing bloodflow to affected area

  THIS CAUSES REDNESS

  • Histamines also increase permeability of capilleries
  • Allows fluid + WBC to leak into tissue

  CAUSES SWELLING

  • Phagocytes move to site of infection
  • Engulf + digest pathogens in phagocytosis
• What do interferons do?

  • Inhibits viral protein synthesis
  • So virus cant replicate + spread via cell lysis
• Describe phagocytosis

  • Phagocytes recognise antigens on pathogens
  • Phagocytes move around pathogens
  • Engulf it in a phagosome
  • Lysosomes have hydrolytic enzymes
  • Lysosome fuse with phagosome
  • Releases enzymes
  • Break down pathogen