Lesson 3

• Proteins aka proteios means “of first importance”
• Friedrich Miescher


  proteins from pus cells
• Friedrich Miescher


  Protein was isolated from nucleus and called it DNA
• Ernst Haeckel


  Discovered most obvious cellular component; nucleus
• Edmund Wilson


  Used staining technique and discovered most important element which is DNA
• Frederick Griffith 


  Did transformation experiment using Streptococcus pneumoniae
• Frederick Griffith 


  Declared presence of transforming principle
• Frederick Griffith 


  Transformed avirulent (R) strain to virulent (S)
• Oswald Avery, Colin Macleod, Maclyn McCarty


  Identified Transforming principle (TP) was DNA