1. Get a piece of chromatography paper
2. Draw an origin line in pencil
3. Add a spot of the substance to be separated to the origin line
4. Place the paper in a solvent with the origin line above the solvent
5. Solvent moves up the chromatography paper
6. Substance dissolves into the solvent
7. More soluble substances move further up the paper
8. Substances with different solubilities move up the paper different amounts, separating them