1. In skin bleeding time, tissue and blood vessels play an important part in stopping flow of blood; whereas in coagulation time, there is no blood vessel factor and tissue actor are minimal.
2. In skin bleeding time, the character of the clot is all important, for a feeble, poorly adherent and non-retractile clot is incapable of closing the wound adequately and is swept away by flowing blood as fast as it is formed. In coagulation time, the strength of the clot and its ability to retract are not involved.