Neuropathology Ia

• Transtentorial Herniation on the 3rd cranial nerve causes papillary dilation
• In transtentorial herniation the posterior cerebral artery is affected leading to ischaemic injury of the primary visual cortex
• The most common site of embolic stroke is the middle cerebral artery.
• Arterio - venous malformations are characterised by having a tangled network of worm - like valvular channels
• Vasogenic odema cause accumulation in the extracellular space
• Cytotoxic odema has a microscopic finding of perineuronal swelling of astrocytic processes
• Transtentorial herniation = compression of contralateral cerebral peduncle against tentorium = kernohan's notch