Bio Explan For OCD

• SSRI


  Selective seratonin reuptake inhibitor
• SSRI


  SSRIs work on the serotonin system in the brain
• Anti-depressants: SSRIs


  •Serotonin is released by certain neurons in the brain. It is released by the presynaptic neurons and travels across a synapse
• Anti-depressants: SSRIs


  The neurotransmitter chemically conveys the signal from the presynaptic neuron to the postsynaptic neuron. If it is not absorbed by the postsynaptic neuron then it will be reabsorbed by the presynaptic neuron where it is broken down.
• Anti-depressants: SSRIs


  •By preventing the re-absorption and breakdown of serotonin SSRIs effectively increase its levels in the synapse and thus continue to stimulate the postsynaptic neuron. This will then increase serotonin levels being absorbed by the postsynaptic neuron
• Ssri medication


  •Dosage and other advice vary according to which SSRI is prescribed. A typical daily dose of Fluoxetine is 20mg - although this may be increased if it is not benefiting the patient.••The drug is available as capsules or liquid. It takes three to four months of daily use for SSRIs to have much impact on symptoms.•
• Combining SSRIs with other treatments

  •Drugs are often used alongside cognitive behaviour therapy (CBT) to treat OCD.
• CBT


  •The drugs reduce a patient's emotional symptoms, such as feeling anxious or depressed. This means that patients can engage more effectively with the CBT.•In practice some people respond best to CBT alone whilst others benefit more from drugs like Fluoxetine
• Tricyclics

  •Are an older type of antidepressant which are sometimes used, such as Clomipramine.•These have the same effect on the serotonin system as SSRIs.
• Tricyclics


  •These are a second line of defence for patients who don't respond to SSRIs.•They have more severe side-effects than SSRIs so it is generally kept in reserve for patients who do not respond to SSRIs.