Morphology

• Which of the following is the primary route of infection for Acanthamoeba?

  a)Inhalation of contaminated airb) Ingestion of contaminated food or waterc) Skin contact with contaminated surfacesd) Injection of contaminated substances

  Skin contact with contaminated surfaces
• What species of Acanthamoeba has the potential to cause infections in humans?

  = Acanthamoeba polyphaga

  = Acanthamoeba castellanii

  = Acanthamoeba culbertsoni

  = Acanthamoeba hatchetti
• What is the characteristic appearance of the cyst wall in Acanthamoeba?

  Jogged outer wall
• How does the motility of Acanthamoeba trophozoites compare to Naegleria fowleri trophozoites?

  Acanthamoeba trophozoites are more motile
• True or False: Acanthamoeba trophozoites contain obvious peripheral chromatin.

  False
• What techniques has been used for the identification of Acanthamoeba?

  = PCR assay

  = Monoclonal antibody testing

  = Flow cytometry
• What is the size range of Acanthamoeba trophozoites?

  20-30 µm
• Which organelle is responsible for the sluggish motility of Acanthamoeba trophozoites?

  Pseudopods
• What is the primary target organ of Acanthamoeba infections in humans?

  Brain
• True or False: Acanthamoeba infections are commonly transmitted from person to person.

  False
• Which of the following is NOT a symptom of Acanthamoeba keratitis?

  a)Eye painb) Blurred visionc) Photophobiad) Coughing

  Coughing
• Acanthamoeba cysts are equipped with a double cell wall. What is the appearance of the inner wall?

  Smooth
• How does the size of Acanthamoeba cysts compare to trophozoites?

  Cysts are smaller than trophozoites
• True or False: Acanthamoeba infections are typically treated with antibiotics.

  False
• What is a potential complication of Acanthamoeba infections?

  = Meningitis

  = Encephalitis

  = Keratitis