[PMPT] Lesson 6 and 7: Biosafety, Biosecurity, and Biorisk

• Prevention from accidental exposure

  Biosafety
• Aims in protecting the public health and environment from accidental exposure to biological agents

  Biosafety
• Aims in protecting the public health and environment from accidental exposure to biological agents
• Prevention from deliberate exposure

  Biosecurity
• Deals with the preventions of misused intentional releases of pathogens, toxins and other biological materials

  Biosecurity
• A biohazard is an agent of biological origin that has the capacity to produce deleterious effect on humans
• A biohazard is an agent of biological origin that has the capacity to produce deleterious effect on humans
• Individuals who handle and process microbiological specimen are vulnerable to pathogenic microorganisms
• Individuals who handle and process microbiological specimen are possible source of LAI. What is LAI?

  Laboratory Acquired Infectious
• Laboratory biosafety and biosecurity traces its history in North America and Western Europe.
• The origins of biosafety is rooted in the US Biological Weapons Program which began in 1943.
• The biosafety was ordered by the US President Franklin Roosevelt
• Biosafety was active during the cold war
• In 1969, US President Richard Nixon terminated the US Biological weapons program
• Where was the assigned place of installation for biological research and development?

  Camp Detrick
• Biosafety was an inherent component of biological weapons development
• Who designed the modifications for biosafety at camp detrick?

  Newell A. Jonhson
• Consequent meetings eventually led to the formation of the ABSA in1984. What is ABSA stands for?

  American Biological Safety Assoiciation
• Ventilated Cabinets are early progenitors to the nearly ubiquitous engineered control now known as the biological biosafety cabinet
• In 1909, a pharmaceutical company in Pennysylvania developed a ventilated cabinet to prevent infection from mycobacterium tuberculosis
• The increasing mortality and morbidity due to small fox in 1967, WHO aggressively pursued the eradication of the virus
• What are the two consolidated virus stocks made by World Health Assembly?

  CDC and SCRVB Vector
• What is CDC stands for?

  Center of Disease Control and Prevention
• Where is CDC located?

  USA
• What is SRCVB Vector stands for?

  State Research Center Virology and Biotechnology Vector
• In 1974, CDC published the classification of Etiological Agents on the basis of hazards.
• Where is SRCVB located?

  Russia
• National Institute of Health of the United States published the NIH Guidelines for Research Involving Recombinant DNA Molecules.
• WHO's first edition of Laboratory Biosafety Manual in 1984,
• CDC and NIH's jointly published first edition of the Biosafety in Microbiological and Biomedical Laboratories manual in 1984.
• He is the pioneer of biosafety that provide the foundation for evaluating the risk of handling infectious biological hazards

  Arnold Wedum
• In 1966, Wedum and Morton Reitman analyzed multiple epidemiological studies of laboratory-based outbreaks
• In 1996, the US government enacted Select Agent Regulation
• Anthrax Attacks of 2001, also known as Amerithrax
• It is a tier agent that pose the greatest risk of deliberate misuse and remaining select agents

  Tier 1 agents
• Bacillus Anthracis - Anthrax
• Yersinia Pestis - Plague
• Clostridium Botulinum - Botulism
• Variola Major - Smallpox
• Ebola and Marburg Viruses - Viral hemorrhagic fever