Stimulation of thyroid gland: ● (Thyroxine output)
Increased rate of cellular metabolism (chemical thermogenesis)
Stimulation of SNS: ● EPINEPHRINE, NOREPINEPHRINE & SYMPATHETIC STIMULANTS
Increased metabolism
Increase in Body Temp (Fever): - Increased metabolic rate
For every 1℃ increase, 12% increase in chemical reaction
Heat is LOST THROUGH: Radiation, conduction, convection, evaporation
RADIATION
transfer of heat from one surface to another without contact between surfaces
CONDUCTION
transfer of heat from one molecule to another & that are in contact with one another
- Ex. body immersed in cold water
CONVECTION
Dispersion of heat through air currents
- Ex. opening windows in a hot room
EVAPORATION
Vaporization of moisture from the respiratory tract & from mucosa of the mouth and the skin leads to insensible water loss, thus, leading to insensible heat loss (10%-basal heat loss)
- When body temp increases, vaporization accounts for greater heat loss
- Diaphoresis visible respiration
Factors Affecting Body Temperature
● Age
● Diurnal variations (circadian rhythms)
● Exercise
● Hormones
● Stress
● Environment
Alterations in Body Temperature:
Pyrexia, hyperthermia, fever
Hyperpyrexia
Hypothermia
Heat stroke
Heat exhaustion
Pyrexia, hyperthermia, fever
● Above normal
● 38° - 40°C
Hyperpyrexia
● Very high fever
● 41°C and above
Hypothermia
● Subnormal or below normal level of core temperature
● Severe hypothermia
○ decreased rate of heat production
○ Sleepiness and coma
○ Further depress the activity of heat control mechanisms
● 3 physiologic mechanisms of Hypothermia::
a. Excessive what loss
b. Inadequate heat production to counteract heat loss
c. Impaired hypothalamic thermoregulation
Heat stroke
● Prolonged exposure to sun or high environmental temperatures
● Signs and symptoms:
○ Hot, dry skin (due to hypothalamic malfunction)
○ Confusion
○ Delirium
○ Muscle cramps
○ Nausea
○ Very high fever as high as 45°C
○ Increased heart rate
○ Excess thirst
○ Visual disturbances
○ incontinence
Heat exhaustion
● Occurs when there is profuse diagnosis resulting to excess water and electrolyte loss
● Signs and symptoms:
○ Diaphoresis
○ Hypotension
○ Weakness
○ Normal pulse
FOUR TYPES OF FEVER
Intermittent
Remittent
Relapsing (me)
Constant
Intermittent
Alternate fever & normal temp
- Ex. malaria
Remittent
Fluctuations (more than 2℃) occurs over the 24 hr period but remains above normal (cold or influenza)
Relapsing (me)
Febrile for a few days then with 1 or 2 days normal temperature
Constant
Temperature fluctuations minimally but consistently above normal
- Ex. typhoid fever
Fever strike temperature that rises to fever level rapidly following a normal temperature, returns to normal within few hours
Ex. bacterial blood infections
TEMPERATURE: Lifespan Considerations
Infants
Unstable
Newborns must be kept warm to prevent hypothermia
2. Children
Tympanic or temporal artery sites preferred
3. Elders
Tends to be lower than that of middle-aged adults
CLINICAL MANIFESTATIONS (Temp)
ONSET (Cold or chill stage)
PLATEAU (Course)
DEFERVESCENCE
ONSET (Cold or chill stage)
● Complaints of feeling cold cyanotic nail beds gooseflesh appearance of the skin cessation of sweating