Cells of the Connective Tissues

• What is the MOST COMMON CELLS in connective tissue proper?

  fibroblast
• What produces and maintain most of the tissue’s extracellular components?

  Fibroblast
• What does fibroblast synthesize and secrete? (2)

  collagen and elastic
• What is the most common protein in the body?

  Collagen
• True or false: Fibroblast have a small inactive nuclei?

  False; large active
• Fibroblast have EOSINOPHILIC cytoplasm.
• What shape are the fibroblasts?

  Spindle-shaped
• What type of cell is LYMPHOCYTE-DERIVED?

  Plasma Cell
• Plasma cell is responsible for the synthesis of IMMUNOGLOBULIN and ANTIBODIES.
• What is the average life span of Plasma cells?

  10-20 days
• Plasma cell has a BASOPHILIC cytoplasm
• Plasma cell: "clock-face" appearance
• Plasma cells contains large clumps of HETEROCHROMATIN
• Adipocytes is also known as what?

  fat cells
• Adipocytes are specialized for cytoplasmic storage of LIPID as NEUTRAL FATS, or less commonly for the production of HEAT.
• Adipocytes: signet-ring appearance
• Brown adipose: functions for thermoregulation of babies
• White adipose: fat storage for adult humans
• Adipocytes has circular LIPIDS in the MIDDLE.
• Leukocytes is also known as what?

  White blood cells
• Inflammation: vascular and defensive responsible to injury or foreign substances.
• Where is leukocytes produced from?

  red bone marrow
• Which cells has a PHAGOCYTIC ABILITY?

  Macrophages
• What is the size of a macrophage?

  10-30 micrometer
• Which cell has a kidney-shaped nucleus?

  Macrophage
• Macrophage is sometimes referred to as what?

  histiocytes
• Macrophages: ingest or phagocytize bacteria
• What type of cell responds to pulmonary TB?

  Macrophages
• Dust cells: lungs
• Kupffer cells: liver
• Langerhan cell: skin
• Microglia: brain
• Dendritic cells: lymph nodes
• Mast cells: oval or irregularly shaped cells
• What are the size of mast cells?

  7-20 micrometer
• Metachromasia: blue to purple or red
• Mast cells are filled with BASOPHILIC SECRETORY GRANULES.
• Which cells releases localized release of many BIOACTIVE SUBSTANCES like heparin, histamine, serine proteases, eosinophil and neutrophil, cytokines, and phospholipids?


  Mast cells
• Location of MONOCYTE?

  Blood
• Location of MACROPHAGE?


  Connective tissue, lymphoid organs, lungs, bone marrow, pleural and peritoneal cavities