•However, functional plasticity tends to reduce with age. The brain has a greater propensity for reorganisation in childhood as it is constantly adapting to new experiences and learning.•During infancy, the brain experiences a rapid growth in the number of synaptic connections it has, peaking at approximately 15,000 at 2-3 years. As we age, rarely used connections are deleted and frequently used connections are strengthened. This process is called synaptic pruning.