CR/krebs

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n r

Cards (11)

  • 2. Acetyl-CoA + oxaloacetate -> citrate. CoA released
  • 3. citrate rearranged into isocitrate.
  • 4. isocitrate -> a-ketoglutarate via decarboxylation & reduction of NAD+
  • 5. a-ketoglutarate -> succinyl-CoA. CoA-SH added, decarboxylation & reduction of NAD+
  • 6. succinyl-CoA -> succinate. ATP created via [GDP->GTP catalyzes ADP+P=ATP], CoA-SH released
  • 7. succinate -> fumarate. reduction of FADH
  • 8. fumarate rearranged into malate.
  • 9. malate -> oxaloacetate. reduction of NAD+
  • 1 (2 is really step 1 this is PyOx). pyruvate -> acetyl-CoA. decarboxylation, reduction of NAD+, CoA added to two carbon atoms to create acetyl-CoA
  • Cycle turns twice for every glucose molecule oxidized to produce 4 CO2, 2 ATP, 6 NADH, 2 FADH2
  • acetyl-CoA enters the cycle and combines with oxaloacetate to form 6 carbon compound citrate.