Translation regulation

Cards (7)

  • RNA interference (RNAi)

    The process of regulating translation
  • RNAi
    • Occurs in eukaryotic and some prokaryotic organisms
    • Involves targeting particular mRNA sequences to inhibit certain genes
  • RNAi mechanism
    1. Transcribed mRNA is destroyed in the cytoplasm before it can be used to code for a polypeptide chain
    2. Double-stranded RNA is cut into small interfering RNA (siRNA) by enzymes
    3. siRNA becomes single-stranded and binds to RISC enzyme
    4. siRNA-enzyme complex binds complementary mRNA and cuts the target mRNA, preventing translation
  • Transcription
    The process that results in the production of mRNA
  • Translation
    The process where mRNA is used to code for a polypeptide chain
  • Translational control

    The regulation of protein synthesis by preventing the mRNA from being translated
  • RNAi disrupts and destroys the mRNA that has been transcribed, turning off the corresponding gene and preventing the polypeptide chain from being made