Nephrons take filtrate of the blood and form urine
Main task is to maintain homeostatic balance of plasma and excrete potential toxins
Nephrons filter, reabsorb, and secrete
Also adjust BP, RBC production, and calcium absorption
Renal corpuscle – high pressure glomerulus pushes solutes through filtration slits and into the Bowman's capsule, filtration slits match up with fenestrations along capillary
Bowman's capsule forms a lumen and directs fluid to the Proximal Convoluted Tubule (PCT)
10-20% of plasma filters through the filtration slits
Fenestrations prevent blood cells and large proteins from passing out of glomerulus
Proteins associated with pores are slightly negative so more positive substances can get