Cleavage - Fertilization initiates embryotic development allowing cleavage to take place. Cleavage is the rapid series of mitotic cell divisions of the developing embryo leading to multicellular ball mass. In mammals, this continuously happens as the embryo transverses the oviduct toward the uterus. Once more than 100 cells are present, the embryo is now a blastocyst, characterized by having a distinct inner cell mass, which eventually forms the fetus.