PHYL1002

• Bone marrow produces WBC
• Monocytes are in blood
• Macrophages are in tissue
• Lymphocytes are in the acquired immune system
• B-cells are in antibody-mediated
• Cytotoxic T cells are in cell-mediated
• Basophils are in blood
• Mast cells are in tissue
• Helper T cells activate cytotoxic T cells and B cells
• Loss of lymphatic filtration is called lymphedema
• MHC class I are found on body cells and cell surface
• HIV targets Helper T cells which activate acquired immune system
• Perforin makes holes
• Granzyme induces apoptosis
• Antigen-presenting cells: Macrophage, B cell, dendritic cell
• Blood doping decreases blood flow because it increases viscosity
• Plateau of fast AP is due to influx of ca2+
• Dilating arterioles decreases blood pressure
• SV = EDV - ESV
• Calcium moves into cell during plateau of contractile cells and depolarization of autorhythmic cells
• P wave is atrial depolarization
• QRS wave is ventricular depolarization
• T wave is ventricular repolarization
• Edema is excess fluid in interstitial space
• K+ decreases HR
• In parasympathetic, ACh binds to muscarinic on SA node
• Parasympathetic decreases slope of pacemaker potential
• Relaxing smooth muscles increases blood flow
• Increasing TPR decreases blood flow
• Carotid measure blood flow to brain
• Aortic measure blood flow to body
• Only the sympathetic nervous system innervates the ventricular myocardium
• Vasoconstriction increases resistance and decreases blood flow
• decreased after load = more blood ejected
• CVCC is in medulla oblongata
• Type 1 alveolar cells are for gas exchange
• Type 2 alveolar cells are for surfactant production
• Branchoconstriction decreases radius and increases resistance
• If FEV is less than 80% it's obstructive
• If FEV is more than 80% it's restrictive