Bloodloss was still a major problem during surgery in the late 1800s.
Now that doctors had anaesthetics and antiseptics, they often attempted more complex operations. l.
JamesBlundell had carried out the first human blood transfusion in 1818. Because blood could not be stored for later use, early transfusions involved the donor being directly connected to the recipient by a tube.
Blundell performed 10 transfusions in total – 5 were successfull
Scientists knew that certain chemicals could stop bloodclotting when it leaves the body, but these could also have sideeffects like convulsions.
KarlLandsteiner discovered the first 3blood groups (A, B and O) in 1901.
This made bloodtransfusions more successful because it stopped the donor’s blood being rejected by the recipient’s body.