1. Pulmonary Circuit: blood flows through right atrium to right ventricle through pulmonary trunk to arteries to carry blood to lungs to become oxygenated then pumped back to the heart
2. Systemic Circuit: blood returned to left atrium pumped to left ventricle and out to the body
Mandates that the heart is able to match cardiac ejection tot the dynamic changes occurring in ventricular filling and thereby regulates ventricular contraction and ejection