Practice Quiz

• Only adaptive Immune responses are enhanced during reinfection
• Macrophages produce RNS
• Lymph Nodes

  First site where a blood bourne pathogen is detected
• Bone marrow is not supplied by blood and lymph
• M-CSF promotes the growth and differentiation of Macrophages
• G-CSF promotes the growth and differentiation of Neutrophils
• Eosinophils are derived from CMP progenitors
• Alpha-Defensin


  Antimicrobial Peptide
• Antimicrobial peptides do not bind to positively charged proteins in the cytoplasm and interfere with protein trafficking in the cell
• Fungi


  Zymosan is found on which class of microbe?
• Heat shock protein is an example of a DAMP
• Viruses

  Single Stranded RNA
• TLR9 recognizes dsDNA
• TLR7 recognizes ssRNA commonly found in viruses
• C9


  The MAC consists of a multimeric complex of which of the following proteins that, by their association, forms a pore in the surface of the attacked cell?
• IL-8


  Promotes chemotaxis of neutrophils into injured/infected tissues
• IFN alpha activates NK cells
• Acute phase Proteins are produced by the Liver
• MHC I is expressed on surface of a T cell
• MHC class II has two transmembrane regions
• Treg


  A defect in which of the following helper T cell types can lead to inflammatory bowel disease?
• CTLs induce apoptosis in infected target cells much the same way that NK cells do 
• The TCR and CD8 co-receptor on a CTL binds MHC class I containing endogenous peptides, and is expressed on all nucleated cells.
• Intracellular Pathogens


  If you are deficient in cytotoxic T cells, what group of pathogens would you be susceptible to?
• Swollen organelles: characteristic of necrotic death
• 10% of lymphocytes do not go to the lymph nodes or spleen
• Which molecules direct lymphocytes to the appropriate peripheral tissues?

  Chemokines, Selectins, and Integrins
• Repeated viral infection suggests a deficiency in what type of immunity?

  T Lymphocyte
• Which cytokines produce Treg cells?

  TGF-B