Introduction of law to restrict goods, people ad capital to move. This is done to protect people
Instability
If a business tries to operate or expand into a political unstable country, there are some economic risks that needs to be considered.
Major trading sources
Because the UK was removed from the EU, the UK has to go through lots of security measures in order to sell and buy products and services internationally.
Change in government
Different governments and political parties could have different views and attitudes towards business activity and related legislation.
(E.g. Trump versus Biden. Biden may not be so friendly with countries such as North Korea.)