If patient is on mechanical ventilator
1. Place SVN on the inspiratory limb at not more than 18 inches away from the patient wye
2. Dilute drug with NSS (4 ml is ideal) and set flows to 6-8 LPM for O2 or air driven in-line nebulization
3. Adjust ventilator flow to maintain pretreatment settings (do not forget to return settings after treatment!!)