When fungi accidentally penetrate host barriers, or when immunologic conditions exist that favour fungi entry and growth
Key features of a virus
Small, have DNA or LNA genomes, obligate intracellular parasites
How do viruses cause disease?
By killing important cells or disrupting cell function
Key features of a protist
Eukaryotic, have mitochondria, they can be parasites, aquatic, unicellular
How do protists cause disease?
Feed off another organism causing harm
How can diseases be transmitted in animals?
Air (including droplet infections), direct contact, water, contaminated food, insect vectors, cuts/blood, sexual intercourse
Symptoms/Transmission/Treatment of measles
-Fever and skin rash
-The virus is spread by inhalation of droplets from coughing and sneezing
-Isolation
Symptoms/Transmission/Treatment of HIV
-Mild flu like illness to begin with, then remains hidden in the immune system
-Spread by direct sexual contact and exchange of bodily fluids
-vaccination
Symptoms/Transmission/Treatment of Tobacco Mosaic Virus
-Causes a distinctive 'mosaic' pattern of discolouration on the leaves. This leads to lack of growth
-By contact between plant material which is diseased and healthy plants
-There is no treatment
Symptoms/Transmission/Treatment of Salmonella
-Fever, abdominal cramps and vomiting
-Bacteria that lives in the guts of animals, found in raw meat
-Vaccination
Symptoms/Transmission/Treatment of Gonorrhoea
-In the early stages, yellow or green discharge, pain during urination
-Unprotected sex
-Antibiotics
Symptoms/Transmission/Treatment of Rose Black Spot
-Purple or black spots develop on the leaves. They often turn yellow or drop early
-Spores of fungus spread in the environment carried by wind
-Removing and burning affected leaves
Symptoms/Transmission/Treatment of Malaria
-Affects the liver and red blood cells. Recurrent episodes of shaking. Can be fatal
-Female mosquito, who bites one human and then another
-Drugs
Define 'Immune System'
A complex network of organs cells and proteins that defends the body against infection
Define 'Antibody'
A blood protein produced in response to and counteracting a specific antigen
Define 'Antitoxin'
An antibody that counteracts a toxin
Define 'Phagocytosis'
The ingestion of bacteria or other material by phagocytes and amoeboid protozoans
What is the functioning order of the immune system?
Pathogens enter the blood-steam > Lymphocytes produces antibodies/antitoxins > Antibodies bind to antigens on pathogens > Phagocytes of pathogens or toxins
What happens if blood doesn't clot properly?
Scabs wont form as quickly, easier for pathogens to get in through the cut
Explain the function of antibodies and antitoxins
They bind to pathogens and clump them together to stop them getting into cells
Explain the function of memory cells
Leftin your bloodstream after a vaccination or infection. They cause a quicker immune response and produce lots of antibodies.
What is the primary immune response
The first time the immune system encounters a pathogen
What is the secondary immune response?
The second time the immune system encounters a pathogen
Why will antibodies be produced quicker if the same bacteria infect the body again?
Because of memory cells recognising the pathogen
What is a vaccination
An injection of dead or weakened pathogens or antigens of the pathogens