Chronic obstructive pulmonary disorder characterized by airflow limitations and inflammation caused by high exposure to noxious particles, gases, and smoking
Chronic bronchitis
Characterized by a chronic productive cough that lasts for 3 months per year over 2 years
Irritant exposure such as smoking or pollution generates an inflammatory response in the bronchioles
Chronic inflammatory response stimulates goblet cells to increase in size and number (mucous gland hyperplasia) causing mucus hypersecretion
Chronic inflammation can also cause structural changes such as thickening of the bronchi walls, fibrosis, and smooth muscle hypertrophy, which narrow the airways making it hard to breathe
Increased mucus and irritant exposure cause cilia destruction and therefore impairs mucociliary clearance, increasing infection risk and obstruction of the airways
Emphysema
Chronic inflammation due to irritant exposure leads to the release of the enzyme elastase, which breaks down the elastic fibers in the alveoli walls
This results in alveoli losing the recoil function and causes air trapping and hyperinflation
The destruction of alveoli reduces the surface area available for gas exchange leading to hypoxemia and hypercapnia
Signs and symptoms of COPD
Persistent productive cough
Shortness of breath
Wheezing
Frequent respiratory infections
Signs and symptoms of emphysema
Shortness of Breath (Dyspnea)
Chronic Cough
Wheezing
Tightness of chest
Barrel chested
Cyanosis
Risk factors for COPD
Smoking
Occupational Exposure to Lung Irritants
Indoor Air Pollution
Genetics
Age
Smoking effects on the lungs
Airway Irritation and Inflammation
Alveolar Damage
Decreased Lung Elasticity
Increased Mucus Production
Activation of Protease Enzymes
Diagnostic tests for COPD
Spirometry
Peak Expiratory Flow (PEF) Measurement
Chest X-ray
Computed Tomography (CT) Scan
Arterial Blood Gas (ABG) Analysis
Pulmonary Function Tests (PFTs)
Six-Minute Walk Test
COPD treatment
Cessation of smoking
Bronchodilators – long and short acting
Inhaled corticosteroids
Breathing exercises
Oxygen therapy
Dietary advice
Immunisations
A multi-disciplinary approach is required
Complications of COPD
Respiratory Infections
Acute Exacerbations
Cor Pulmonale
Pulmonary Hypertension
Depression and Anxiety
Osteoporosis
Malnutrition
Sleep Disorders
Decreased Exercise Tolerance
Nursing management of COPD
Dyspnoea
Ineffective airway clearance
Inability to carry out ADLs – activity intolerance