DDS SDF Pt. II

• Tablet - Solid Dosage form which may or may not contain medicinal substances with or without diluents and prepared either by compression or molding
• Tablet


  Solid dosage form which may or may not contain medicinal substances with or without diluents and prepared either by compression or molding
• Tablet press


  Tablets are compressed using?
• grooved or scored


  marking in tablet depending on the design of punches and dies
• Caplets


  capsule-shaped tablets that allow the product to be smaller than a capsule filled with an equivalent amount of powder
• Boluses


  large tablets intended for veterinary use
• Coated Tablets


  Type of tablet that has outer covering or coating
• Sugar Coating


  Type of tablet that is coated with sugar layer that is colored or uncolored
• Sugar Coating


  Type of Coated Process that is water soluble coating
• Sugar Coating


  Type of Coating that is water soluble and quickly dissolved after swallowing
• Steps in sugar coating

  • Sealing
  • Subcoating
  • Smooting
  • Color Coating/ Syruping
  • Finishing / Polishing
• Sealing


  Step in Sugar Coating that primarily prevents the premature erosion or disintegration of the tablet
• Subcoating


  Most critical step in sugar coating and uses gummy coating solution to help the sugar solution to adhere na mas okay sa tablet
• Subcoating


  step in sugar coating that used to improve the bond between the sealed coat and the sugar coat
• Tablet Weight


  adds 50-100% of its weight
• Subcoating


  Steps in SUgar coating that Alternate Layers of Gums or Dusting Powders Happens to avoid or prevent
• Gelatin Acacia Solution and dusting powders (talc, calcium carbonate)


  Materials used in subcoating
• Smoothing


  First step before you add color and sugar in solution
• Color Coating / Syruping


  For completion and finalizing of rounding off the tablet and smoothing the coatings. Is also critical because it gives the tablets its color and elegance
• Polishing / Finishing


  Attained the final smoothness and desired shines of the tablets. We also employs addition of waxes to provide coating shines and glossy such as beeswax, chlorinated wax, carnauba wax, candelilla wax, and paraffin wax'
• Film Coating


  Type of Coated Tablet that is coated with a thin layer of polymer
• Gelatin Coated Tablets


  Coated with a layer of gelatin
• Gelcaps


  also knows as caplet and coated with a thin layer of gelatin that allows the coated product to be about 1/3 smaller than capsule filled with the same amount of powder
• Film Former used in Non-aqueous (Organic) Film Coating Solution

  • Hydroxypropyl methylcellulose
  • Ethylcellulose
  • Polyvinyl alcohol
• Plasticizer used in Non-Aq (organic) film coating

  • Polyethylene glycol
  • Glycerin
  • propylene glycol
• Opaquant and Colorant used in non-aq organic film coating

  • Titanium Dioxide (Op)
  • FD & C and C&D dyes (colorant)
• Film former used in aq film coating solution

  cellulose ether polymers:

  • hydroxypropyl methylcellulose
  • methylcellulose
• Plasticizer used in aq film coating solution

  • Gylcerin
  • Propylene glycol
  • diethyl phthalate
• colorant used in aq film coating solution

  • Titanium dioxide
  • FD & C dyes
  • D&C dyes
• water


  vehicle used in aq film coating solution
• Enteric Coating


  for tablets intended to pass through the stomach intact to disintegrate and release drug content for absorption in the small intestine
• Enteric Coating


  design to be resistance to acid condition making it based on factors in pH
• Fluid Bed or Suspension Coating


  spray coating of powders, granules beads, pellets, or tablets held in suspension by a column of air
• Components of Fluid Bed or Suspension Coating

  • Top Spray
  • Bottom spray
  • Tangential Spray
• Compression Coating


  Similar to multiple coated compressed tablets having an inner core and an outer shell drug material
• Compression coating


  Core tablets may be sugar coated by compression
• Compression coating


  anhydrous operation and may be safely employed in the coating of tablets containing drugs labile to moisture
• Uncoated or Plain Tablets


  Tablets made by compression of powders or granules without any additional coating and can consist of one or more API
• Multiple Compressed Tablet


  Tablets prepared by more then one compression cycle resulting to a multilayered tablet or tablet-within-a-tablet
• Chewable Tablets


  pleasant-tasting tablets formulated to disintegrate smoothly in the mouth with or without chewing