Also known as the resting phase of the cell cycle; interphase is the time during which the cell prepares for division by undergoing both cell growth and DNA replication. It occupies around 95% time of the overall cycle. The interphase is divided into three phases: G1 phase (Gap 1) - G1 phase is the phase of the cell between mitosis and initiation of replication of the genetic material of the cell. During this phase, the cell is metabolically active and continues to grow without replicating its DNA. S phase (Synthesis) - DNA replication takes place during this phase. If the initial quantity of DNA in the cell is denoted as 2N, then after replication it becomes 4N. However the number of chromosomes does not vary, viz., if the number of chromosomes during G1 phase was 2n, it will remain 2n at the end of S phase. The centriole also divides into two centriole pairs in the cells which contain centriole. G2 phase (Gap 2) - During this phase, the RNA, proteins, other macromolecules required for multiplication of cell organelles, spindle formation, and cell growth are produced as the cell prepares to go into the mitotic phase.