Unit 6

Cards (8)

  • 3 Types of filaments
    1. Actin
    2. Microtubules
    3. Intermediate filaments
  • Actin
    Cell surface shape & movement. Actin filaments and microtubules are composed of globular subunits
  • Microtubules
    Intracellular transport, positioning of organelles
  • Intermediate filaments
    Mechanical strength. Composed of elongated and fibrous subunits. Resistant to tearing
  • Protofilaments
    Long linear strings of filament subunits joined end to end
  • Nucleation

    Multiple subunit-subunit contacts lead to rapid elongation by addition of more subunits
  • Critical concentration
    Concentration at which monomeric subunits are in equilibrium with polymer. Here, rate of subunit addition=rate of subunit loss
  • Treadmilling
    Polymer maintains a constant length, even though there is a net flux of subunits through the polymer. Happens at an intermediate subunit concetration, where growth of plus end is equal to shrinkage at minus end