≥3 yr, High flow; 0.24-1 FDO2, Precise FiO2; good for transport; ease of application, Low relative humidity; pressure necrosis to face; difficult to fit and maintain on active child, not recommended for infants; risk of aspiration
Premature infants to adult, Low flow; 25 ml/min–6.0 L/min, Tolerated well by all ages, Inaccurate FiO2; low relative humidity; excessive flows may cause inadvertent CPAP in infants; precise FiO2 may be achieved with O2 blender
Newborns ≤28 days, <0.40 FiO2, combine use with cannula or hood for precise FiO2, Low FiO2 for stable infants; neutral thermal environment for premature infants, Varying FiO2; long stabilization time; limits access to child for patient care
Premature infants to ≤6 mo, 0.21-1 FiO2 with O2 blender maintained at 30° C to 34° C, Warmed and humidified gas at stable FiO2 during routine patient care, Overheating may cause apnea and dehydration; underheating may cause O2 consumption; inadequate flow causes CO2 buildup; noise produced by humidification device may cause hearing loss
Infants to toddlers, High flow; 0.21-0.40 FiO2, Allows child movement, high humidity, cool temperatures, Isolation of child from family; wet bedding and clothes; difficult to maintain stable FiO2; risk of cross-contamination; limits patient care