is a theory stating that genetic info flows only in one direction, from DNA, to RNA, to protein, or RNA to protein directly
central dogma theory
discovery of DNA structure by James Watson and Francis Crick
1953
francis crick proposes the central dogma concept, describing the flow of genetic information from DNA to RNA proteins
1957
Sydney Brenner, Francois Jacob, and Jacques Monod study gene expression in bacteria, elucidating the role of mRNA in transcription
1961
advancements in understanding translation, including the decoding of mRNA by ribosomes and the role of tRNA in bringing amino acids
1960s-1970s
discovery of exceptions to the central dogma, such as retroviruses that reverse transcribe RNA to DNA
1970s-1980s
further exploration of genetic processes, including the discovery of non-coding RNAs and regulatory mechanisms that modulate gene expression and protein function