a decreased physiologic response to the repeated administration of a drug or chemically related substance. Excessive Increase in the dosage is required in order to maintain the desired therapeutic effect
it is due to biochemical changes in the body tissues, especially the nervous system. These tissues come to require the substance for normal functioning. Also called "physical dependence".
effects of one drug are modified by the prior or concurrent administration of another drug, thereby increasing or decreasing the pharmacological action.
-This site is suitable for children over 1 year and adults.
-Position the client in side-lying with the knee bent and raised slightly toward the chest to help locate the ventrogluteal site more easily.
-To locate the site, the nurse places the heel of the hand on the client's greater trochanter, with the fingers pointing toward the client's head.
-With the index finger on the client's anterior superior illiac spine, the nurse stretches the middle finger dorsally (toward the buttocks), palpating the iliac crest.
-This site is composed of the thick gluteal muscles of the buttocks.
-The site should not be used for children under 3 years old unless the child has been walking for at least 1 year.
-The midwife must choose the site carefully to avoid striking the sciatic nerve major blood.
-Avoid hitting the sciatic nerve to prevent paralysis known as "sciatica paralysis".
-The nurse palpates the posterior superior iliac spine, then draws an imaginary line to the greater trochanter of the femur. This line is lateral to and parallel to the sciatic nerve.