Effects of temp and ph on enzymes

• As we increase temperature the activity of the enzyme increases
• At a certain temperature the enzyme is working at its fastest rate this is the optimum temperature
• As we increase the temperature past its optimum the activity of the enzyme rapidly decreases to zero
• At high temperatures the enzyme molecules vibrate and the shape of the active site changes now the substrate no longer fits perfectly the enzyme is denatured
• the enzyme has an optimum ph where the activity is maximum
• If we make the ph more acidic or more alkaline then the activity drops to zero that’s because the active site denatures
• Enzymes in the stomach work best in more acidic ph
• Enzymes in the small intestines work best in an alkaline ph