Pathogenesis

Cards (23)

  • Pathogenesis
    The development of a disease
  • Infection
    The invasion and multiplication of microorganisms in body tissues
  • Infectious disease
    A disease caused by the invasion of the body by pathogenic microorganisms
  • 4 stages of infection
    1. Incubation period
    2. Prodromal period
    3. Period of illness
    4. Convalescent period
  • Localized infection
    An infection confined to a specific area of the body
  • Systemic infection
    An infection that spreads throughout the body
  • Acute disease
    A disease with rapid onset and rapid recovery
  • Give examples of a Acute diseases
    • measles
    • mumps
    • influenza
  • Chronic disease
    A disease with slow onset and long duration
  • Give example of Chronic diseases
    • tuberculosis
    • leprosy
    • syphilis
  • Subacute disease
    A disease more sudden than chronic but less sudden than acute
  • Give example of Subacute diseases
    • subacute bacterial endocarditis (SBE)
  • Sign
    An objective indication of a disease that can be observed by a doctor
  • Symptom
    A subjective indication of a disease that is experienced by the patient
  • Gonorrhea
    • Usually symptomatic in male patients, asymptomatic in female patients
  • Trichomoniasis
    • Usually symptomatic in female patients, asymptomatic in male patients
  • Latent infection
    An infection where the pathogen remains dormant within the host's cells
  • Herpes
    • The virus remains dormant within cells of the nervous system until triggered
  • Virulence
    The degree of pathogenicity of a microorganism
  • Virulence factors

    Characteristics that contribute to a pathogen's ability to cause disease
  • Give examples of Signs
    Heart sound
    Breath Sound
    Blood pressure
    Temperature
    Lab results
    Pulse Rate
    Swelling
    Rashess/Redness
  • Give example of Symptoms
    Ache/Pain
    Ringing of Ears
    Blurred Vision
    Nauseous
    Dizziness
    Itching
    Chills
  • Give the reason WHY INFECTION DOES NOT ALWAYS RESULT TO DISEASE?

    * The microbe may land at an anatomical site where it is unable to multiply.

    If microbes land at a site where specific receptor sites are absent, they are unable to cause disease.

    • Antibacterial factors may be present.

    • The indigenous microbiota of that site may inhibit growth of the foreign microbes.

    • The individual's nutritional and overall health status often influences the outcome of the pathogen-host encounter.

    • The person may be immune to that particular pathogen.

    • WBCs may engulf or destroy the pathogen.