The first tube collected with a butterfly will underfill because of the air in the tubing. If the tube contains an additive, the blood-to-additive ratio will be affected. If an additive tube is the first tube to be collected, it is important to draw a few milliliters of blood into a nonadditive tube or another additive tube of the same type and to discard it prior to collecting the first tube. This is referred to as collecting a "clear" or discard tube and is especially critical when one is collecting coagulation tubes using a butterfly