splicing of RNA

Cards (3)

  • what is splicing
    the removal of non-coding sequences (introns) from the primary transcript or pre-mRNA
  • the splicing process
    the introns are looped out and cut off by a complex of proteins and small nuclear RNAs called the spliceosome
    the coding sequences or exons are then joined together to form the final mRNA molecule
    it enables one gene to produce different proteins, depending on which exons are included or excluded increasing proteins
  • the significance
    the various processes involved in gene expression, including transcription, splicing, translation and post-translation modification, allow the cell to make a wide range of proteins needed for its specific functions
    errors in any of these stages could lead to the production of faulty proteins having implications for health and diseases