PT1

• Blood Donation Facilities


  Perform compatibility testing & prepare blood components, screen donors, draw blood, perform testing, deliver components to hospital blood bank
• Blood Donation Facilities (alternative)


  Collect and screen donors only, blood will be processed in blood bank or blood center
• Blood Donation


  1. Collecting whole blood (RBC, plasma, WBC, platelet) from donor within 15 mins using gauge 16-18 needle

  2. Collecting specific component and returning unused component to the donor within 45 mins to 2 hrs
• Donors


  • Autologous donors
  • Allogeneic donors (Voluntary Non-Remunerated, Directed, Paid)
• Autologous donors


  Collect blood 5 to 6 weeks preceding a scheduled surgery, no later than 72 hours before, for autologous use only
• Direct donation


  Collecting shed blood from the surgical site, processing the blood, reinfusing the blood
• Most autologous blood is used to treat surgical blood loss in very specific situations where there is a reasonable opportunity to avoid homologous transfusions or when compatible allogeneic blood is not available
• Directed donors


  The tag for the directed unit is a distinct color (e.g., yellow, salmon), if the donor is a blood relative the unit must be irradiated to prevent graft versus host disease
• Donor Screening Components


  • Donor Registration
  • Medical History
  • Physical Examination
  • Informed Consent
• Donor History Questionnaire

  • Feeling healthy and well today?
  • Currently taking an antibiotic?
  • Currently taking any other medication for an infection?
  • Have you taken any medications on the Medication Deferral List in the time frames indicated?
  • Have you read the educational materials today?
  • Have you taken aspirin or anything that has aspirin in it in the past 48 hours?
  • Have you donated blood, platelets, or plasma in the past 8 weeks?
  • Have you had any vaccinations or other shots in the past 8 weeks?
  • Have you had contact with someone who was vaccinated for smallpox in the past 8 weeks?
  • Have you donated a double unit of red cells using an apheresis machine in the past 16 weeks?
  • Have you had a blood transfusion in the past 12 months?
  • Have you had a transplant such as organ, tissue, or bone marrow in the past 12 months?
  • Have you had a graft such as bone or skin in the past 12 months?
  • Have you come into contact with someone else's blood in the past 12 months?
  • Have you had an accidental needle stick in the past 12 months?
  • Have you had sexual contact with anyone who has HIV/AIDS or has had a positive test for the HIV/AIDS virus?
  • Have you had sexual contact with a prostitute or anyone else who takes money or drugs or other payment for sex?
  • Have you had sexual contact with anyone who has ever used needles to take drugs or steroids, or anything not prescribed by their doctor?
  • Male donors: Have you had sexual contact with another male?
  • Female donors: Have you had sexual contact with a male who had sexual contact with another male in the past 12 months?
  • Have you had sexual contact with a person who has hepatitis?
  • Have you lived with a person who has hepatitis?
  • Have you had a tattoo?
  • Have you had ear or body piercing?
  • Have you had or been treated for syphilis or gonorrhea?
  • Have you been in juvenile detention, lockup, jail, or prison for more than 72 consecutive hours?
  • Have you been outside the United States or Canada in the past 3 years?
  • From 1980 through 1996, did you spend time that adds up to 3 months or more in the United Kingdom?
  • From 1980 through 1996, were you a member of the U.S. military, a civilian military employee, or a dependent of a member of the U.S. military?
  • From 1980 through 1996, did you spend time that adds up to 5 years or more in Europe?
  • Have you ever received a blood transfusion in the United Kingdom or France?
  • Female donors: Have you ever been pregnant or are you pregnant now?
  • Have you ever had a positive test for the HIV/AIDS virus?
  • Have you ever used needles to take drugs, steroids, or anything not prescribed by your doctor?
  • Have you ever received money, drugs, or other payment for sex?
  • Have you ever had malaria?
  • Have you ever had Chagas disease?
  • Have you ever had babesiosis?
  • Have you ever received a dura mater (or brain covering) graft or xenotransplantation product?
  • Have you ever had any type of cancer, including leukemia?
  • Have you ever had any problems with your heart or lungs?
  • Have you ever had a bleeding condition or a blood disease?
  • Have any of your relatives ever had Creutzfeldt-Jakob disease?
• Types of Deferrals


  • Temporary Deferral
  • Indefinite Deferral
  • Permanent Deferral
• Temporary Deferral


  Prospective donor is unable to donate blood for a limited period of time
• Temporary Deferral


  • Donor has received a blood transfusion; defer for 12 months from date of transfusion
  • Donor received vaccination for yellow fever; defer for 2 weeks from date of vaccination
• Indefinite Deferral


  Prospective donor is unable to donate blood for someone else for an unspecified period of time due to current regulatory requirements
• Indefinite Deferral


  • Donor states they have lived in England for 1 year in 1989; defer indefinitely
• Permanent Deferral


  Prospective donor will never be eligible to donate blood for someone else
• Permanent Deferral


  • Donor states that he or she has hepatitis C; defer permanently
• Permanent or Indefinite Deferral (AABB)


  • History of viral hepatitis after eleventh birthday
  • Confirmed positive test for hepatitis B surface antigen
  • Reactive test to antibodies to hepatitis B core on more than one occasion
  • Present or past clinical or laboratory evidence of infection with hepatitis C virus, human T-cell lymphotropic virus, or HIV
  • History of babesiosis or Chagas disease
  • Skin lesions
  • Family history of CJD
  • Risk of VCJD
  • Recipient of dura mater or human pituitary growth hormone
  • Use of a needle to administer nonprescription drugs
• Deferral Periods for Potential Transfusion-Transmitted Infections (AABB)


  • History of Malaria (3 years)
  • Lived in endemic area for 5 consecutive years (3 years from departure)
  • Travel to endemic area (1 year from departure)
  • Leishmaniasis (1 year from departure)