Hollow, muscular, four-chambered (left and right atria, and left and right ventricles) organ
Located in the middle of the thoracic cavity between the lungs in the space called the mediastinum
About the size of a clenched fist
Weighs approximately 255 g (9 oz) in women and 310 g (10.9 oz) in men
Extends vertically from the left second to the left fifth intercostal space (ICS)
Extends horizontally from the right edge of the sternum to the left midclavicular line (MCL)
Can be described as an inverted cone
Upper portion, near the left second ICS, is the base
Lower portion, near the left fifth ICS and the left MCL, is the apex