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Biology Paper 1
SB5 - Health, Disease and the Development of Medicines
Monoclonal Antibodies
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Monoclonal Antibodies:
Mouse injected with
pathogen
to create
immune
response
Mouse specific
B lymphocytes
taken (produce specific
antibodies
)
Fused with
tumour
cell from lab (
fast-dividing
) -
hybridoma
cell produced
Screened
and
antibodies
are extracted
Uses of Monoclonal Antibodies:
Pregnancy
Tests - pregnancy
hormone
binds to
antibodies
and cause
colour
change
Cancer
Diagnosed
- put in
tracers
and when contact cancer cells bind to
tumour
markers
Cancer
Treatment
- carry
anti-cancer
drug straight to tumour markers
targeting
them
Blood Clots
- bind to
proteins
that join together to make a blood clot, are
tracers