endogenous pathway

• VLDL is first lipoprotein to leave liver; what liver manufactures 
• origin of triglycerides found in VLDLs can either be manufactured by the liver or be dietary triglycerides that have been removed from chylomicrons and deposited into VLDL
• in the endogenous pathway, once VLDL reaches tissues, capillary lipase will hydrolyze VLDL for fuel or turn it back to triglycerides and store it (similar to exogenous pathway)
• VLDL will also give up their phospholipids and their proteins
• some VLDL will become LDL
• some VLDL will become remnants of VLDL; remnants will be absorbed by the liver and be recycled
• LDL will give up some of their triglycerides, phospholipids in capillary bed and will be absorbed by cells with LDL receptors