Biological explanation for OCD

    avatar
    Created by
    :)

    Cards (3)

    • Lewis (1936) observed that of his OCD patients, 37% had parents with OCD and 21% had siblings with OCD. This suggests that there is a genetic factor and that OCD could be heritable.
    • What have twin studies shown on the biological explanation for OCD?
      Nestaat (2010)
      Reviewed twin studies and that found that 68% of MZ twins shared OCD compared to 31% of DZ twins.
      This can help us assume that OCD is genetically based because the degree of concordance is significantly higher (and almost double) in MZ than DZ twins.
    • What are candidate genes and what do they show about OCD?
      Genes found to be more prevalent in OCD people.
      OCD is found to be polygenic: up to 230 genes may be involved in OCD.
    See similar decks