Spinal Mechanism

• Spinal Mechanism:

  • manual therapy is non-threatening mechanical stimuli, which the A-Beta fibres are responsive to
  • A-Beta is responsive to non-noxious stimuli
  • A-Beta fibres directly inhibits dorsal horn cell
  • they excite inhibitory interneurons that also inhibit the dorsal horn cell
  • A-Beta fibres are faster than nociceptors, so get to the dorsal horn cell first
• Spinal Cord Mechanism:

  • This mechanism involves the transmission and processing of pain signals within the spinal cord
  • When mechanical stimulation is applied, it can activate inhibitory interneurons within the spinal cord, which can inhibit the transmission of pain signals from the peripheral nerves to the brain
  • Additionally, mechanical stimulation can trigger the release of neurotransmitters, such as gamma-aminobutyric acid (GABA), glycine, and opioids, within the spinal cord, which can further inhibit pain transmission