This mechanism involves the sensory nerves and receptors located in the periphery of the body, such as the skin, muscles, and joints
Mechanical stimulation can activate specialized sensory receptors, such as mechanoreceptors, which can inhibit the transmission of pain signals
Additionally, the activation of mechanoreceptors can trigger the release of neurotransmitters, such as enkephalins and endorphins, which act locally to reduce pain sensation
Moreover, mechanical stimulation can lead to the release of inflammatory mediators, which can modulate pain perception
