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MICROBIOLOGY & PARASITOLOGY
INTEGUMENTARY DISEASES
Chicken Pox
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Varicella Zoster
- It causes chicken pox.
Chicken pox - Also known as
Varicella.
Most common in winter and spring
Blisters
- Small and sit on an area of red skin that can be anywhere and they are varying size.
Giovanni
Filipino
- Discovered chicken pox during the 15th century in Italy.
Richard
Morton
- Gave the name chicken pox.
William
Heberden
- Proved that chicken pox is different from small pox.
Varicella
Zoster
Virus
Also known as human herpesvirus 3 (HHV3)
Varicella Zoster Virus - belongs to the
herpesvirus
family
Viral
Glycoproteins
- the envelope interspersed by spike in varicella zoster virus.
Chicken pox
- primary lesion
Herpes Zoster
- reactivated lesion
Pathogenesis
Day
0-3
: Infection of conjunctivae and mucosa of the upper respiratory tract.
Viral
replication
in regional lymph nodes.
Day
4-6
: primary viremia, viral infection in liver, spleen and other organs.
Day
10-12
: secondary viremia.
Day
14
: infection of skin and appearance of vesicular rash.
Transmission of chicken pox
Inhalation
Droplets
Stages
Incubation period usually
14-17
days.
Prodromal (
1-3
days).
Vesicles.
Pustules.
Scabs.
Recovery typically
7
days after rash appears.
Small
Blister-like
Lesions
occasionally involve the oral side mucosa chiefly the buccal mucosa, tongue, gums and palate as well as the mucosa of the pharynx.
Mucosal
Lesion
initially slightly raised vesicles with surrounding
erythema
, rupture soon after formation and form
small eroded ulcers
with a red margin.
Increased Risk of Complications of Chicken Pox:
Normal Adults
Immunocompromised
Pregnant Woman
Varicella
Vaccine
Contains live varicella virus.
Side effect of vaccine includes redness and soreness at the site of injection.
First Dose of Chicken pox vaccine
12-15
months of age.
Second dose of chicken pox vaccine
4-6
years of age
People
not
been
vaccinated
earlier
People 13 years of age and older should get 2 doses at least
28
days apart.