Help to reduce pain signals. Includes morphine, codeine, Vicodin, heroin, opium, and others. Opiates mimic the body's own natural endorphin actions and are extremely addictive- causing dependence within a few weeks. Produce an intense "rush" of pleasure, as well as block pain. Withdrawal symptoms include hot and cold flashes, cramps, sweating, and shaking that may last from 4 to 7 days, but not life-threatening. Risk of overdose