The movement of blood from the heart to the lungs for oxygenation, then back to the heart again
Systemic circulation
The movement of blood from the heart through the body to provide oxygen and nutrients to the tissues of the body while bringing deoxygenated blood back to the heart
The human circulatory systems are a double circulatory system. It has two separate circuits and blood passes through the heart twice: pulmonary and systemic circulation.
Pulmonary circulation
1. Blood from the body enters the right atrium
2. Pumped through the tricuspid valve into the right ventricle
3. Pumped through the pulmonary valve and into the pulmonary artery
4. Pulmonary artery splits into the right and left pulmonary arteries and the blood travels to each lung
Systemic circulation
1. Oxygenated blood enters the left atrium from the pulmonary veins
2. Pumped through the mitral valve into the left ventricle
3. Pumped through the aortic valve and into the aorta
4. Aorta branches into major arteries to the upper and lower body
Arteries branch into smaller arteries, arterioles, and finally capillaries. Gas and nutrient exchange with the tissues occurs within the capillaries that run through the tissues.
Systemic circulation keeps the metabolism of every organ and every tissue in the body alive, except the parenchyma of the lungs, which are supplied by pulmonary circulation.
Cardiac cycle
The period of time that begins with contraction of the atria and ends with ventricular relaxation
Systole
The period of contraction that the heart undergoes while it pumps blood into circulation
Diastole
The period of relaxation that occurs as the chambers filled with blood
Both the atria and ventricles undergo systole and diastole, and it is essential that these components be carefully regulated and coordinated to ensure blood is pumped efficiently to the body.
Auscultation
Listening to various internal sounds using a stethoscope
Lub
The sound created by the closing of the atrioventricular valves during ventricular contraction
Dup (or Dub)
The sound of the closing of the semilunar valves during ventricular diastole
Murmur
An unusual sound coming from the heart that is caused by the turbulent flow of blood
Systolic blood pressure
The pressure exerted by the blood during ventricular contraction
Diastolic blood pressure
The pressure exerted by the blood during ventricular relaxation or filling
Normal systolic blood pressure is less than 120 mmHg. Normal diastolic blood pressure is less than 80 mmHg.
Arteries
Blood vessels that transport blood away from the heart
Capillaries
Blood vessels where gas and nutrient exchange with the tissues occurs
Veins
Blood vessels that transport blood back to the heart
Plasma makes up about half of the content of the blood and contains proteins, glucose, and other dissolved nutrients.
Blood components
Red blood cells
White blood cells
Platelets
Red blood cells (erythrocytes)
Cells that transport oxygen from the lungs to the tissues and carbon dioxide away
Red blood cells
Lack a nucleus, allowing more space for hemoglobin
Biconcave shape for larger surface area
Thin cell membrane for rapid gas diffusion
Flexible membrane to squeeze through capillaries
White blood cells (leukocytes)
Cells that are part of the immune system, seeking out and destroying foreign pathogens
Types of white blood cells
Neutrophils
Lymphocytes
Platelets (thrombocytes)
Cell fragments that play an essential role in blood clotting
Plasma
The yellow tinted fluid that transports blood cells and contains proteins, nutrients, and other dissolved substances
Plasma makes up 55 percent of our blood volume.
Blood grouping depends on the antigens present on the surface of red blood cells.