cc lec renal function

• 3 sources of creatinine : glycine, arginine and methionine
• azotemia is the elevation of urea in the blood
• urea is the npn with the highest concentration in the blood
• urea is the major excretory product of protein metabolism
• creatinine is a waste product formed by creatine and creatine phosphate in the muscle
• uric acid is a catabolized purine nucleic acid
• the catabolism of guanine and adenosine makes uric acid
• Hypoxanthine-guanine phosphoribosyltransferase - lesch nyhan syndrome
• tophi formation is the formation of uric acid crystals
• free water clearance, mosenthal , fishberg, osmolality and osmolarity - TUBULAR REABSORPTION TEST
• PAH, titratable activity, urinary ammonia : TUBULAR SECRETION AND RENAL BLOOD FLOW TEST
• urea clearance test, creatinine cL, inulin cystatin c- GLOMERULAR FILTRATION TEST
• inulin clearance - gold standard